Article
Translating neoadjuvant therapy into survival benefits: one size does not fit all.
Nature reviews. Clinical oncology - 1 Sept 2016
De Mattos-Arruda Leticia, Shen Ronglai, Reis-Filho Jorge S, Cortés Javier
Abstract excerpt
Neoadjuvant therapy has been established as an effective therapeutic approach for patients with locally advanced breast cancer. Similar outcomes between neoadjuvant and adjuvant chemotherapy have been demonstrated in several trials. Nevertheless, neoadjuvant therapy has some advantages over adjuvant therapy, including tumour downstaging, in vivo assessment of therapeutic efficacy, reduced treatment durations, and...
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