Article
Identification of a New Broadly Cross-reactive Epitope within Domain III of the Duck Tembusu Virus E Protein.
Scientific reports - 8 Nov 2016
Li Chenxi, Bai Xiaofei, Meng Runze, Shaozhou Wulin, Zhang Qingshan, Hua Ronghong, Liu Jyung-Hurng, Liu Ming, Zhang Yun
Abstract excerpt
In 2010, a pathogenic flavivirus termed duck Tembusu virus (DTMUV) caused widespread outbreak of egg-drop syndrome in domesticated ducks in China. Although the glycoprotein E of DTMUV is an important structural component of the virus, the B-cell epitopes of this protein remains uncharacterized. Using phage display and mutagenesis, we identified a minimal B-cell epitope, 374EXE/DPPFG380, that mediates binding to a...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
