Article
Functional Genomic Characterization of Cancer Genomes.
Cold Spring Harbor symposia on quantitative biology - 1 Jan 2016
Howard Thomas P, Vazquez Francisca, Tsherniak Aviad, Hong Andrew L, Rinne Mik, Aguirre Andrew J, Boehm Jesse S, Hahn William C
Abstract excerpt
International efforts to sequence cancer genomes now provide an overview of the major genetic alterations that occur in most human cancers. These studies have identified many highly recurrent alterations in specific cancer subtypes but have also identified mutations that occur at lower frequency and unstudied variants of known cancer-associated genes. To elucidate the function of such cancer alleles, we have...
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