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Article

Human Adaptation of Ebola Virus during the West African Outbreak.

Cell - 3 Nov 2016

Urbanowicz Richard A, McClure C Patrick, Sakuntabhai Anavaj, Sall Amadou A, Kobinger Gary, Müller Marcel A, Holmes Edward C, Rey Félix A, Simon-Loriere Etienne, Ball Jonathan K

Abstract excerpt

The 2013-2016 outbreak of Ebola virus (EBOV) in West Africa was the largest recorded. It began following the cross-species transmission of EBOV from an animal reservoir, most likely bats, into humans, with phylogenetic analysis revealing the co-circulation of several viral lineages. We hypothesized that this prolonged human circulation led to genomic changes that increased viral transmissibility in humans. We...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 27814505
DOI: 10.1016/j.cell.2016.10.013
PMCID: PMC5101188

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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