Article
The Modular Adaptive Ribosome.
PloS one - 1 Jan 2016
Yadav Anupama, Radhakrishnan Aparna, Panda Anshuman, Singh Amartya, Sinha Himanshu, Bhanot Gyan
Abstract excerpt
The ribosome is an ancient machine, performing the same function across organisms. Although functionally unitary, recent experiments suggest specialized roles for some ribosomal proteins. Our central thesis is that ribosomal proteins function in a modular fashion to decode genetic information in a context dependent manner. We show through large data analyses that although many ribosomal proteins are essential...
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