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Article

Is FGF13 a major contributor to genetic epilepsy with febrile seizures plus?

Epilepsy research - 1 Dec 2016

Rigbye Kristin A, van Hasselt Peter M, Burgess Rosemary, Damiano John A, Mullen Saul A, Petrovski Slavé, Puranam Ram S, van Gassen Koen L I, Gecz Jozef, Scheffer Ingrid E, McNamara James O, Berkovic Samuel F, Hildebrand Michael S

Abstract excerpt

Mutation of fibroblast growth factor 13 (FGF13) has recently been implicated in genetic epilepsy with febrile seizures plus (GEFS+) in a single family segregating a balanced translocation with a breakpoint in this X chromosome gene, predicting a partial knockout involving 3 of 5 known FGF13 isoforms. Investigation of a mouse model of complete Fgf13 knock-out revealed increased susceptibility to...

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Source

Identifiers

PMID: 27810516
DOI: 10.1016/j.eplepsyres.2016.10.008

Genes

FGF13

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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