Article
[Conformational polymorphysm of G-rich fragments of DNA ALU-repeats. I. Potential noncanonical structures].
Biomeditsinskaia khimiia - 1 Jul 2016
Sekridova A V, Varizhuk A M, Tatarinova O N, Severov V V, Barinov N A, Smirnov I P, Lazarev V N, Klinov D V, Pozmogova G E
Abstract excerpt
In this paper, we report results of systematic studies of conformational polymorphism of G-rich DNA fragments from Alu repeats. Alu retrotransposones are primate-specific short interspersed elements. Using the Alu sequence from the prooncogen bcl2 intron and the consensus AluSx sequence as representative examples, we determined characteristic Alu sites that are capable of adopting G-quadruplex (GQ) conformations...
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