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Synthetically derived bat influenza A-like viruses reveal a cell type- but not species-specific tropism

24 Oct 2016

Abstract excerpt

Two novel influenza A-like viral genome sequences have recently been identified in Central and South American fruit bats and provisionally designated "HL17NL10" and "HL18NL11." All efforts to isolate infectious virus from bats or to generate these viruses by reverse genetics have failed to date. Recombinant vesicular stomatitis virus (VSV) encoding the hemagglutinin-like envelope glycoproteins HL17 or HL18 in...

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PMID: 27791106
DOI: 10.1073/pnas.1608821113

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