Article
Whole genome sequencing for M/XDR tuberculosis surveillance and for resistance testing.
Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases - 1 Mar 2017
Walker T M, Merker M, Kohl T A, Crook D W, Niemann S, Peto T E A
Abstract excerpt
Whole genome sequencing (WGS) can help to relate Mycobacterium tuberculosis genomes to one another to assess genetic relatedness and infer the likelihood of transmission between cases. The same sequence data are now increasingly being used to predict drug resistance and susceptibility. Controlling the spread of tuberculosis and providing patients with the correct treatment are central to the World Health...
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