Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Role of DNA Methylation in the Metabolic Memory Phenomenon Associated With the Continued Progression of Diabetic Retinopathy

27 Oct 2016

Abstract excerpt

PURPOSE: Clinical and experimental studies have shown that diabetic retinopathy progression does not halt after termination of hyperglycemia, suggesting a "metabolic memory" phenomenon. DNA is highly dynamic, and cytosine methylation changes can last for several years. In diabetes, DNA methylation regulates expression of many genes associated with retinal mitochondrial homeostasis. Our aim was to investigate the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Epigenetics and DNA Methylation
Share to Retinal Diseases and Treatments
Share to Retinal Imaging and Analysis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 27787562
DOI: 10.1167/iovs.16-19759

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Role of DNA Methylation in the Metabolic Memory Phenomenon Associated With the Continued Progression of Diabetic RetinopathyPMID 27787562Read ↗

Mitochondria DNA Replication and DNA Methylation in the Metabolic Memory Associated with Continued Progression of Diabetic RetinopathySemantic proximity Read ↗

Epigenetic Modification of Mitochondrial DNA in the Development of Diabetic RetinopathySemantic proximity Read ↗

Targeting epigenetic modifications as a potential therapeutic option for diabetic retinopathySemantic proximity Read ↗

DNA methylation in diabetic retinopathy: pathogenetic role and potential therapeutic targetsSemantic proximity Read ↗

Novel insights into DNA methylation and its critical implications in diabetic vascular complicationsSemantic proximity Read ↗

Diabetic retinopathy: reversibility of epigenetic modifications and new therapeutic targetsSemantic proximity Read ↗

Role of histone modification and DNA methylation in signaling pathways involved in diabetic retinopathySemantic proximity Read ↗

DNA methyltransferase expression (DNMT1, DNMT3a and DNMT3b) as a potential biomarker for anti-VEGF diabetic macular edema responseSemantic proximity Read ↗

Epigenetic Mechanisms in the Pathogenesis of Diabetic RetinopathySemantic proximity Read ↗

Diabetic retinopathy, metabolic memory and epigenetic modificationsSemantic proximity Read ↗

Epigenetics: deciphering its role in diabetes and its chronic complicationsSemantic proximity Read ↗

Contribution of epigenetics in diabetic retinopathySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.