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Article

Infantile Hemangioma Originates From A Dysregulated But Not Fully Transformed Multipotent Stem Cell

27 Oct 2016

Abstract excerpt

Infantile hemangioma (IH) is the most common tumor of infancy. Its cellular origin and biological signals for uncontrolled growth are poorly understood, and specific pharmacological treatment is unavailable. To understand the process of hemangioma-genesis we characterized the progenitor hemangioma-derived stem cell (HemSC) and its lineage and non-lineage derivatives. For this purpose we performed a...

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PMID: 27786256
DOI: 10.1038/srep35811

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