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Article

Endothelial and circulating C19MC microRNAs are biomarkers of infantile hemangioma

7 Sept 2016

Abstract excerpt

Infantile hemangioma (IH) is the most common vascular tumor of infancy, and it uniquely regresses in response to oral propranolol. MicroRNAs (miRNAs) have emerged as key regulators of vascular development and are dysregulated in many disease processes, but the role of miRNAs in IH growth has not been investigated. We report expression of C19MC, a primate-specific megacluster of miRNAs expressed in placenta with...

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PMID: 27660822
DOI: 10.1172/jci.insight.88856

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