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Article

HEB silencing induces anti-proliferative effects on U87MG cells cultured as neurospheres and monolayers

21 Oct 2016

Abstract excerpt

Glioblastoma multiforme (GBM) is a lethal tumor and novel strategies are required to overcome resistance. Transcription factor 12 (HEB) has been associated with neural and stem cell proliferation, is overexpressed in certain tumor types and is induced in irradiated U87MG cells. The present study aimed to determine whether HEB knockdown, with or without irradiation, may sensitize GBM cells. U87MG GBM and ACBRI‑371...

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Identifiers

PMID: 27779678
DOI: 10.3892/mmr.2016.5877

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