Article
Should epitope-based HLA compatibility be used in the kidney allocation system?
Human immunology - 1 Jan 2017
Duquesnoy Rene J
Abstract excerpt
The new kidney allocation system (KAS) still applies donor-recipient HLA compatibility mostly at the antigen level and although some four-digit alleles have been included. This system is used to record unacceptable mismatches for sensitized transplant candidates with serum HLA antibodies. Since the reactivities of such antibodies are specifically associated with epitopes rather than HLA antigens, a more...
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