Article
Latent class analysis reveals clinically relevant atopy phenotypes in 2 birth cohorts.
The Journal of allergy and clinical immunology - 1 Jun 2017
Hose Alexander J, Depner Martin, Illi Sabina, Lau Susanne, Keil Thomas, Wahn Ulrich, Fuchs Oliver, Pfefferle Petra Ina, Schmaußer-Hechfellner Elisabeth, Genuneit Jon, Lauener Roger, Karvonen Anne M, Roduit Caroline, Dalphin Jean-Charles, Riedler Josef, Pekkanen Juha, von Mutius Erika, Ege Markus J
Abstract excerpt
BACKGROUND: Phenotypes of childhood-onset asthma are characterized by distinct trajectories and functional features. For atopy, definition of phenotypes during childhood is less clear. OBJECTIVE: We sought to define phenotypes of atopic sensitization over the first 6 years of life using a latent class analysis (LCA) integrating 3 dimensions of atopy: allergen specificity, time course, and levels of specific IgE...
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