Article
Allergic rhinitis phenotypes with distinct transcriptome profiles in children: A birth cohort.
The Journal of allergy and clinical immunology - 1 May 2024
Shin Youn Ho, Kim Jeong-Hyun, Lee Si-Hyeon, Lee So-Yeon, Park Yoon Mee, Choi Eum Ji, Paek Eun Young, Song Kun-Baek, Park Min Ji, Jung Sungsu, Yoon Jisun, Suh Dong In, Kim Kyung Won, Ahn Kangmo, Hong Soo-Jong
Abstract excerpt
BACKGROUND: Allergic rhinitis (AR) phenotypes in childhood are unclear. OBJECTIVES: This study sought to determine AR phenotypes and investigate their natural course and clinical and transcriptomic characteristics. METHODS: Latent class trajectory analysis was used for phenotyping AR in 1050 children from birth through 12 years using a birth cohort study. Blood transcriptome analyses were performed to define the...
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