Article
Universal Asymptotic Clone Size Distribution for General Population Growth.
Bulletin of mathematical biology - 1 Nov 2016
Nicholson Michael D, Antal Tibor
Abstract excerpt
Deterministically growing (wild-type) populations which seed stochastically developing mutant clones have found an expanding number of applications from microbial populations to cancer. The special case of exponential wild-type population growth, usually termed the Luria-Delbrück or Lea-Coulson model, is often assumed but seldom realistic. In this article, we generalise this model to different types of wild-type...
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