Article
Effect of Age on Melanoma Risk, Prognosis and Treatment Response.
Acta dermato-venereologica - 11 Jul 2018
Ribero Simone, Stucci Luigia Stefania, Marra Elena, Marconcini Riccardo, Spagnolo Francesco, Orgiano Laura, Picasso Virginia, Queirolo Paola, Palmieri Guiseppe, Quaglino Pietro, Bataille Veronique
Abstract excerpt
As for all types of cancer, the incidence of melanoma increases with age. However, naevus counts (the principal risk factor for melanoma) decrease with age; hence the relationship between ageing and melanoma is complex. Subjects who maintain a high naevus count after the age of 50 years are more likely to be affected by melanoma, as their lesions do not senesce. Longer telomere length, which is strongly related...
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