Article
Clinical significance of residual viremia detected by two real-time PCR assays for response-guided therapy of HCV genotype 1 infection.
Journal of hepatology - 1 May 2014
Vermehren Johannes, Aghemo Alessio, Falconer Karolin, Susser Simone, Lunghi Giovanna, Zeuzem Stefan, Colombo Massimo, Weiland Ola, Sarrazin Christoph
Abstract excerpt
BACKGROUND & AIMS: The duration of current standard dual and protease inhibitor-based triple therapies for chronic hepatitis C is determined by assessment of early viral kinetics. Little is known about differences between HCV RNA assays for the use in response guided therapy. METHODS: HCV RNA was assessed by two widely used real-time PCR-based assays, Cobas Ampliprep/Cobas TaqMan (CAP), and Real-Time HCV (ART) in...
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