Article
Comparison of three commercially available assays for HCV RNA using the international unit standard: implications for management of patients with chronic hepatitis C virus infection in clinical practice.
The American journal of gastroenterology - 1 May 2003
Shiffman Mitchell L, Ferreira-Gonzalez Andrea, Reddy K Rajender, Sterling Richard K, Luketic Velimir A, Stravitz R Todd, Sanyal Arun J, Garrett Carleton T, De Medina Maria, Schiff Eugene R
Abstract excerpt
OBJECTIVES: The present study was performed to evaluate the impact of the international unit standard for measuring HCV RNA in the management of patients with chronic hepatitis C virus (HCV) infection. METHODS: The three assays used were Amplicor Monitor PCR, the National Genetics Institute PCR assay, and branched chain DNA. HCV RNA was measured at four time points (baseline, 3 months after the start of therapy,...
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