Article
Systems genetics analysis of pharmacogenomics variation during antidepressant treatment.
The pharmacogenomics journal - 1 Jan 2018
Madsen M B, Kogelman L J A, Kadarmideen H N, Rasmussen H B
Abstract excerpt
Selective serotonin reuptake inhibitors (SSRIs) are the most widely used antidepressants, but the efficacy of the treatment varies significantly among individuals. It is believed that complex genetic mechanisms play a part in this variation. We have used a network based approach to unravel the involved genetic components. Moreover, we investigated the potential difference in the genetic interaction networks...
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