Article
HIRA Gene is Lower Expressed in the Myocardium of Patients with Tetralogy of Fallot.
Chinese medical journal - 20 Oct 2016
Ju Zhao-Ru, Wang Hui-Jun, Ma Xiao-Jing, Ma Duan, Huang Guo-Ying
Abstract excerpt
BACKGROUND: The most typical cardiac abnormality is conotruncal defects (CTDs) in patients with 22q11 deletion syndrome (22q11DS). HIRA (histone cell cycle regulator) gene, as one of the candidate genes located at the critical region of 22q11DS, was reported as possibly relevant to CTD in animal models. This study aimed to analyze the level of expression of the HIRA gene in tetralogy of Fallot (TOF) patients and...
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