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Article

Tetralogy of Fallot: variants of MYH6 gene promoter and cellular functional analyses.

Pediatric research - 1 Jul 2024

Zuo Ji-Yang, Chen Huan-Xin, Yang Qin, Liu Zhi-Gang, He Guo-Wei

Abstract excerpt

BACKGROUND: Tetralogy of Fallot (TOF) is a common form of congenital heart disease. The MYH6 gene has important effects on cardiovascular growth and development. METHODS: In 608 subjects, including 315 TOF patients, we investigated the MYH6 gene promoter variants and verified the effect on gene expression by using cellular functional experiments with three cell lines (HEK-293, HL-1, and H9C2 cells) and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 38135727
DOI: 10.1038/s41390-023-02955-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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