Article
Deciphering the mechanisms of developmental disorders: phenotype analysis of embryos from mutant mouse lines.
Nucleic acids research - 4 Jan 2016
Wilson Robert, McGuire Christina, Mohun Timothy
Abstract excerpt
The Deciphering the Mechanisms of Developmental Disorders (DMDD) consortium is a research programme set up to identify genes in the mouse, which if mutated (or knocked-out) result in embryonic lethality when homozygous, and initiate the study of why disruption of their function has such profound effects on embryo development and survival. The project uses a combination of comprehensive high resolution 3D imaging...
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