Article
Genetic susceptibility for air pollution-induced airway inflammation in the SALIA study.
Environmental research - 1 Jan 2017
Hüls Anke, Krämer Ursula, Herder Christian, Fehsel Karin, Luckhaus Christian, Stolz Sabine, Vierkötter Andrea, Schikowski Tamara
Abstract excerpt
BACKGROUND: Long-term air pollution exposure has been associated with chronic inflammation providing a link to the development of chronic health effects. Furthermore, there is evidence that pathways activated by endoplasmatic reticulum (ER) stress induce airway inflammation and thereby play an important role in the pathogenesis of inflammatory diseases. OBJECTIVE: We investigated the role of genetic variation of...
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