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Article

Associations of the calcium-sensing receptor gene CASR rs7652589 SNP with nephrolithiasis and secondary hyperparathyroidism in haemodialysis patients.

Scientific reports - 14 Oct 2016

Grzegorzewska Alicja E, Paciorkowski Mateusz, Mostowska Adrianna, Frycz Bartosz, Warchoł Wojciech, Stolarek Ireneusz, Figlerowicz Marek, Jagodziński Paweł P

Abstract excerpt

Nephrolithiasis, secondary hyperparathyroidism (sHPT), and cardiovascular complications are associated with disturbances in Ca handling and contribute to morbidity/mortality during haemodialysis (HD). Calcimimetics, activators of the calcium-sensing receptor (CaSR), provide an effective means of reducing parathyroid hormone (PTH) secretion in sHPT. Polymorphism in CaSR gene (CASR) influences Ca-related...

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Share to Cardiovascular Diseases
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

Share to Kidney Failure, Chronic

Share to Nephrolithiasis

Share to Polymorphism, Single Nucleotide

Share to Receptors, Calcium-Sensing

Share to Renal Dialysis

Source

Open in PubMed Open full text

Identifiers

PMID: 27739473
DOI: 10.1038/srep35188
PMCID: PMC5064403

Genes

CASR
PTH
AHR
GLI3
SOX18

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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