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Article

The impact of CASR A990G polymorphism in response to cinacalcet treatment in hemodialysis patients with secondary hyperparathyroidism.

Scientific reports - 9 Sept 2021

Ngamkam Jaruwan, Vadcharavivad Somratai, Areepium Nutthada, Auamnoy Titinun, Takkavatakarn Kullaya, Katavetin Pisut, Tiranathanagul Khajohn, Praditpornsilpa Kearkiat, Eiam-Ong Somchai, Susantitaphong Paweena

Abstract excerpt

The objective of this study was to determine the impact of calcium sensing receptor (CASR) A990G genetic polymorphism on parathyroid hormone (PTH) lowering response to cinacalcet treatment when controlling for significant influencing clinical factors. This retrospective study was conducted on 135 Thai hemodialysis (HD) patients with secondary hyperparathyroidism (SHPT). CASR A990G genotypes were determined. The...

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Identifiers

PMID: 34504264
DOI: 10.1038/s41598-021-97587-8
PMCID: PMC8429569

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