Article
Interleukin-6 and C-reactive protein as prognostic biomarkers in metastatic colorectal cancer.
Oncotarget - 15 Nov 2016
Thomsen Maria, Kersten Christian, Sorbye Halfdan, Skovlund Eva, Glimelius Bengt, Pfeiffer Per, Johansen Julia S, Kure Elin H, Ikdahl Tone, Tveit Kjell Magne, Christoffersen Thoralf, Guren Tormod Kyrre
Abstract excerpt
OBJECTIVES: The aim was to explore the prognostic significance of IL-6 and markers of systemic inflammatory response (SIR), in particular C-reactive protein (CRP), in metastatic colorectal cancer (mCRC) patients, in the total study population and according to RAS and BRAF mutation status. RESULTS: High levels of pretreatment serum IL-6 or CRP were associated with impaired outcome, in terms of reduced PFS and OS....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.