Whole Genome Sequencing Demonstrates Limited Transmission within Identified Mycobacterium tuberculosis Clusters in New South Wales, Australia.

doi:10.1371/journal.pone.0163612

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Topics Community

Back to search

Article

Whole Genome Sequencing Demonstrates Limited Transmission within Identified Mycobacterium tuberculosis Clusters in New South Wales, Australia.

PloS one - 1 Jan 2016

Gurjav Ulziijargal, Outhred Alexander C, Jelfs Peter, McCallum Nadine, Wang Qinning, Hill-Cawthorne Grant A, Marais Ben J, Sintchenko Vitali

Abstract excerpt

Australia has a low tuberculosis incidence rate with most cases occurring among recent immigrants. Given suboptimal cluster resolution achieved with 24-locus mycobacterium interspersed repetitive unit (MIRU-24) genotyping, the added value of whole genome sequencing was explored. MIRU-24 profiles of all Mycobacterium tuberculosis culture-confirmed tuberculosis cases diagnosed between 2009 and 2013 in New South...

Topics

Adolescent
Adult
Cluster Analysis
DNA, Bacterial
Female
Genome, Bacterial
Genotyping Techniques
Humans
Incidence
Male
Middle Aged

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mycobacterium tuberculosis

New South Wales

Phylogeny

Polymorphism, Single Nucleotide

Tuberculosis

Young Adult

Source

Open in PubMed Open full text

Identifiers

PMID: 27737005
DOI: 10.1371/journal.pone.0163612
PMCID: PMC5063377

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Whole Genome Sequencing Demonstrates Limited Transmission within Identified Mycobacterium tuberculosis Clusters in New South Wales, Australia.PMID 27737005Read ↗

Temporal dynamics of Mycobacterium tuberculosis genotypes in New South Wales, Australia.Semantic proximity Read ↗

Identifying Likely Transmission Pathways within a 10-Year Community Outbreak of Tuberculosis by High-Depth Whole Genome Sequencing.Semantic proximity Read ↗

Genotype heterogeneity of Mycobacterium tuberculosis within geospatial hotspots suggests foci of imported infection in Sydney, Australia.Semantic proximity Read ↗

Whole Genome Sequence Analysis of a Large Isoniazid-Resistant Tuberculosis Outbreak in London: A Retrospective Observational Study.Semantic proximity Read ↗

Whole-genome sequencing for rapid, reliable and routine investigation of Mycobacterium tuberculosis transmission in local communitiesSemantic proximity Read ↗

Exploring programmatic indicators of tuberculosis control that incorporate routine Mycobacterium tuberculosis sequencing in low incidence settings: a comprehensive (2017–2021) patient cohort analysisSemantic proximity Read ↗

Tracking and responding to an outbreak of tuberculosis using MIRU-VNTR genotyping and whole genome sequencing as epidemiological tools.Semantic proximity Read ↗

Whole genome sequencing of drug-resistant Mycobacterium tuberculosis isolates in Victoria, Australia.Semantic proximity Read ↗

Value of routine whole genome sequencing for Mycobacterium tuberculosis drug resistance detectionSemantic proximity Read ↗

The use of whole-genome sequencing in cluster investigation of a multidrug-resistant tuberculosis outbreak.Semantic proximity Read ↗

Molecular Epidemiology of Mycobacterium tuberculosis Complex Strains in Urban and Slum Settings of Nairobi, KenyaSemantic proximity Read ↗

Population structure, biogeography and transmissibility of <i>Mycobacterium tuberculosis</i>Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.