Article
Vimentin is important in the neural differentiation of PC12 cells promoted by sialylation.
Glycoconjugate journal - 1 Feb 2017
Wu Li Hui, Shao Xiao Ting, Guo Jun Xia, Sun Hui, Chen Qi, Pan Jing, Cai Qian Qian, Dong Yi Wei, Chen Zhong Yi, Yan Xiao Mei, Peng Min, Zhong Nanbert, Wu Xing Zhong
Abstract excerpt
Sialic acid modification is a kind of post-translational modification. To investigate the regulation effect of sialic acid on neural differentiation, we used CycloManN propanyl perac (CycloManN pro), a metabolic precursor of sialic acid, to treat PC12 cells. We noted that CycloManN pro indeed robustly promoted global sialylation detected by MAL II lectin blot in PC12 cells. Simultaneously, we interestingly found...
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