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Rheumatoid Arthritis Naive T Cells Share Hypermethylation Sites With Synoviocytes

13 Oct 2016

Abstract excerpt

OBJECTIVE: To determine whether differentially methylated CpGs in synovium-derived fibroblast-like synoviocytes (FLS) of patients with rheumatoid arthritis (RA) were also differentially methylated in RA peripheral blood (PB) samples. METHODS: For this study, 371 genome-wide DNA methylation profiles were measured using Illumina HumanMethylation450 BeadChips in PB samples from 63 patients with RA and 31 unaffected...

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PMID: 27723282
DOI: 10.1002/art.39952

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