Article
Functional Characterization of Circulating Mumps Viruses with Stop Codon Mutations in the Small Hydrophobic Protein.
mSphere - 18 Nov 2020
Stinnett Rita Czakó, Beck Andrew S, Lopareva Elena N, McNall Rebecca J, Latner Donald R, Hickman Carole J, Rota Paul A, Bankamp Bettina
Abstract excerpt
Between 2015 and 2017, routine molecular surveillance in the United States detected multiple mumps viruses (MuVs) with mutations in the small hydrophobic (SH) gene compared to a reference virus of the same genotype. These mutations include an unusual pattern of uracil-to-cytosine hypermutations and other mutations resulting in the generation of premature stop codons or disruption of the canonical stop codon. The...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.