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Article

Molecular modelling and molecular dynamics of CFTR.

Cellular and molecular life sciences : CMLS - 1 Jan 2017

Callebaut Isabelle, Hoffmann Brice, Lehn Pierre, Mornon Jean-Paul

Abstract excerpt

The cystic fibrosis transmembrane conductance regulator (CFTR) protein is a member of the ATP-binding cassette (ABC) transporter superfamily that functions as an ATP-gated channel. Considerable progress has been made over the last years in the understanding of the molecular basis of the CFTR functions, as well as dysfunctions causing the common genetic disease cystic fibrosis (CF). This review provides a global...

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Identifiers

PMID: 27717958
DOI: 10.1007/s00018-016-2385-9
PMCID: PMC11107702

Genes

CFTR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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