The rs767649 polymorphism in the promoter of miR-155 contributes to the decreased risk for cervical cancer in a Chinese population.

doi:10.1016/j.gene.2016.10.002

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The rs767649 polymorphism in the promoter of miR-155 contributes to the decreased risk for cervical cancer in a Chinese population.

Gene - 20 Dec 2016

Wang Shizhi, Cao Xiaoli, Ding Bo, Chen Jinfeng, Cui Mengjing, Xu Yuling, Lu Xiaoyun, Zhang Zhengdong, He Aiqin, Jin Hua

Abstract excerpt

Genetic variants in miRNAs have attracted more and more attention these years because they are capable of altering miRNA function and/or expression, consequently affecting downstream biological pathways and disease risk. The rs767649 polymorphism, locating in the promoter of miR-155, was recently reported to be able to alter transcriptional activity of miR-155 and relate to lung cancer risk. In this study, we...

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PMID: 27717891
DOI: 10.1016/j.gene.2016.10.002

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