Article
Disorders of sex development: update on the genetic background, terminology and risk for the development of germ cell tumors.
World journal of pediatrics : WJP - 1 May 2009
Cools Martine, Looijenga Leendert H J, Wolffenbuttel Katja P, Drop Sten L S
Abstract excerpt
BACKGROUND: Considerable progress has been made on genetic mechanisms involved in disorders of sex development and on tumor formation in dysgenetic gonads. Clinical and psychological outcome of patients are, as far as evaluated, unsatisfactory at present. Guidelines are emerging in order to optimize long-term outcome in the future. DATA SOURCES: The information obtained in this review is based on recent original...
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