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Article

Development of a RNA-Seq Based Prognostic Signature in Lung Adenocarcinoma.

Journal of the National Cancer Institute - 1 Jan 2017

Shukla Sudhanshu, Evans Joseph R, Malik Rohit, Feng Felix Y, Dhanasekaran Saravana M, Cao Xuhong, Chen Guoan, Beer David G, Jiang Hui, Chinnaiyan Arul M

Abstract excerpt

Background: Precision therapy for lung cancer will require comprehensive genomic testing to identify actionable targets as well as ascertain disease prognosis. RNA-seq is a robust platform that meets these requirements, but microarray-derived prognostic signatures are not optimal for RNA-seq data. Thus, we undertook the first prognostic analysis of lung adenocarcinoma RNA-seq data and generated a prognostic...

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PMID: 27707839
DOI: 10.1093/jnci/djw200
PMCID: PMC5051943

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EGFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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