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Article

Mitochondrial Carriers Link the Catabolism of Hydroxyaromatic Compounds to the Central Metabolism in Candida parapsilosis.

G3 (Bethesda, Md.) - 7 Dec 2016

Zeman Igor, Neboháčová Martina, Gérecová Gabriela, Katonová Kornélia, Jánošíková Eva, Jakúbková Michaela, Centárová Ivana, Dunčková Ivana, Tomáška L'ubomír, Pryszcz Leszek P, Gabaldón Toni, Nosek Jozef

Abstract excerpt

The pathogenic yeast Candida parapsilosis metabolizes hydroxyderivatives of benzene and benzoic acid to compounds channeled into central metabolism, including the mitochondrially localized tricarboxylic acid cycle, via the 3-oxoadipate and gentisate pathways. The orchestration of both catabolic pathways with mitochondrial metabolism as well as their evolutionary origin is not fully understood. Our results show...

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Source

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Identifiers

PMID: 27707801
DOI: 10.1534/g3.116.034389
PMCID: PMC5144973

Genes

MPC1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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