Article
The precision relationships between eight GWAS-identified genetic variants and breast cancer in a Chinese population.
Oncotarget - 15 Nov 2016
Chen Yazhen, Fu Fangmeng, Lin Yuxiang, Qiu Lin, Lu Minjun, Zhang Jiantang, Qiu Wei, Yang Peidong, Wu Na, Huang Meng, Wang Chuan
Abstract excerpt
Some of the new breast cancer susceptibility loci discovered in recent Genome-wide association studies (GWASs) have not been confirmed in Chinese populations. To determine whether eight novel Single-Nucleotide Polymorphisms (SNPs) have associations with breast cancer risk in women from southeast China, we conducted a case-control study of 1,156 breast cancer patients and 1,256 healthy controls. We first validated...
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