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Article

Urea-Dependent Adenylate Kinase Activation following Redistribution of Structural States.

Biophysical journal - 4 Oct 2016

Rogne Per, Wolf-Watz Magnus

Abstract excerpt

Proteins are often functionally dependent on conformational changes that allow them to sample structural states that are sparsely populated in the absence of a substrate or binding partner. The distribution of such structural microstates is governed by their relative stability, and the kinetics of their interconversion is governed by the magnitude of associated activation barriers. Here, we have explored the...

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Identifiers

PMID: 27705762
DOI: 10.1016/j.bpj.2016.08.028
PMCID: PMC5052468

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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