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Exome Sequencing Reveals Primary Immunodeficiencies in Children with Community-Acquired Pseudomonas aeruginosa Sepsis

20 Sept 2016

Abstract excerpt

One out of three pediatric sepsis deaths in high income countries occur in previously healthy children. Primary immunodeficiencies have been postulated to underlie fulminant sepsis, but this concept remains to be confirmed in clinical practice. Pseudomonas aeruginosa (P. aeruginosa) is a common bacterium mostly associated with healthcare-related infections in immunocompromised individuals. However, in rare cases,...

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PMID: 27703454
DOI: 10.3389/fimmu.2016.00357

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