Article
M2 macrophages do not fly into a "RAGE".
Inflammation research : official journal of the European Histamine Research Society ... [et al.] - 1 Jan 2017
Rojas Armando, Añazco Carolina, Araya Paulina
Abstract excerpt
Tumor-associated macrophages (TAMs) are key elements in orchestrating host responses inside tumor stroma. This population may undergo a polarized activation process, thus rendering a heterogeneous spectrum of phenotypes, where the classically activated type 1 macrophages (M1) and the alternative activated type 2 macrophages (M2) represent two extreme phenotypes. In this commentary, based on very recent research...
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