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Article

Drug repurposing for glioblastoma based on molecular subtypes.

Journal of biomedical informatics - 1 Dec 2016

Chen Yang, Xu Rong

Abstract excerpt

A recent multi-platform analysis by The Cancer Genome Atlas identified four distinct molecular subtypes for glioblastoma (GBM) and demonstrated that the subtypes correlate with clinical phenotypes and treatment responses. In this study, we developed a computational drug repurposing approach to predict GBM drugs based on the molecular subtypes. Our approach leverages the genomic signature for each GBM subtype, and...

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Identifiers

PMID: 27697594
DOI: 10.1016/j.jbi.2016.09.019
PMCID: PMC6146394

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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