Article
Dopamine DRD2 polymorphism (DRD2/ANNK1-Taq1A) is not a significant risk factor in writer's cramp.
Journal of neurogenetics - 1 Jan 2000
Zeuner Kirsten E, Acewicz Albert, Knutzen Arne, Dressler Dirk, Lohmann Katja, Witt Karsten
Abstract excerpt
Writers' cramp is a movement disorder with dystonic co-contraction of fingers and hand during writing and is part of the clinical spectrum of focal dystonias. Previous studies showed reduced striatal dopamine receptor D2 (DRD2) availability in dystonia. The expression of D2 receptors is modulated by a DRD2/ANKK1-Taq1A polymorphism (rs1800497). This study addresses the question of whether the DRD2/ANKK1-Taq1A...
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