Article
The Plasmodium alveolin IMC1a is stabilised by its terminal cysteine motifs and facilitates sporozoite morphogenesis and infectivity in a dose-dependent manner.
Molecular and biochemical parasitology - 1 Jan 2017
Al-Khattaf Fatimah S, Tremp Annie Z, El-Houderi Amira, Dessens Johannes T
Abstract excerpt
Apicomplexan parasites possess a unique cortical cytoskeleton structure composed of intermediate filaments. Its building blocks are provided by a conserved family of proteins named alveolins. The core alveolin structure is made up of tandem repeat sequences, thought to be responsible for the filamentous properties of these proteins. A subset of alveolins also possess conserved motifs composed of three closely...
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