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Article

Dynamic DNA methylation landscape defines brown and white cell specificity during adipogenesis

20 Aug 2016

Abstract excerpt

OBJECTIVE: DNA methylation may be a stable epigenetic contributor to defining fat cell lineage. METHODS: We performed reduced representation bisulfite sequencing (RRBS) and RNA-seq to depict a genome-wide integrative view of the DNA methylome and transcriptome during brown and white adipogenesis. RESULTS: Our analysis demonstrated that DNA methylation is a stable epigenetic signature for brown and white cell...

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Share to Adipokines, Inflammation, and Metabolic Diseases
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Identifiers

PMID: 27689016
DOI: 10.1016/j.molmet.2016.08.006

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