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Article

Phenotyping Tumor Heterogeneity through Proteogenomics: Study Models and Challenges.

International journal of molecular sciences - 14 Aug 2024

Piana Diletta, Iavarone Federica, De Paolis Elisa, Daniele Gennaro, Parisella Federico, Minucci Angelo, Greco Viviana, Urbani Andrea

Abstract excerpt

Tumor heterogeneity refers to the diversity observed among tumor cells: both between different tumors (inter-tumor heterogeneity) and within a single tumor (intra-tumor heterogeneity). These cells can display distinct morphological and phenotypic characteristics, including variations in cellular morphology, metastatic potential and variability treatment responses among patients. Therefore, a comprehensive...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39201516
DOI: 10.3390/ijms25168830
PMCID: PMC11354793

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