Risk of thrombosis according to need of phlebotomies in patients with polycythemia vera treated with hydroxyurea.

doi:10.3324/haematol.2016.152769

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Article

Risk of thrombosis according to need of phlebotomies in patients with polycythemia vera treated with hydroxyurea.

Haematologica - 1 Jan 2017

Alvarez-Larrán Alberto, Pérez-Encinas Manuel, Ferrer-Marín Francisca, Hernández-Boluda Juan Carlos, Ramírez María José, Martínez-López Joaquín, Magro Elena, Cruz Yasmina, Mata María Isabel, Aragües Pilar, Fox María Laura, Cuevas Beatriz, Montesdeoca Sara, Hernández-Rivas José Angel, García-Gutiérrez Valentín, Gómez-Casares María Teresa, Steegmann Juan Luis, Durán María Antonia, Gómez Montse, Kerguelen Ana, Bárez Abelardo, García Mari Carmen, Boqué Concepción, Raya José María, Martínez Clara, Albors Manuel, García Francesc, Burgaleta Carmen, Besses Carlos

Abstract excerpt

Hematocrit control below 45% is associated with a lower rate of thrombosis in polycythemia vera. In patients receiving hydroxyurea, this target can be achieved with hydroxyurea alone or with the combination of hydroxyurea plus phlebotomies. However, the clinical implications of phlebotomy requirement under hydroxyurea therapy are unknown. The aim of this study was to evaluate the need for additional phlebotomies...

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Identifiers

PMID: 27686377
DOI: 10.3324/haematol.2016.152769
PMCID: PMC5210240

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