Article
A prevalent caveolin-1 gene variant is associated with the metabolic syndrome in Caucasians and Hispanics.
Metabolism: clinical and experimental - 1 Dec 2015
Baudrand Rene, Goodarzi Mark O, Vaidya Anand, Underwood Patricia C, Williams Jonathan S, Jeunemaitre Xavier, Hopkins Paul N, Brown Nancy, Raby Benjamin A, Lasky-Su Jessica, Adler Gail K, Cui Jinrui, Guo Xiuqing, Taylor Kent D, Chen Yii-Der I, Xiang Anny, Raffel Leslie J, Buchanan Thomas A, Rotter Jerome I, Williams Gordon H, Pojoga Luminita H
Abstract excerpt
CONTEXT AND OBJECTIVE: We examined whether a prevalent caveolin-1 gene (CAV1) variant, previously related to insulin resistance, is associated with metabolic syndrome (MetS). PATIENTS AND METHODS: We included subjects genotyped for the CAV1 variant rs926198 from two cohorts: 735 Caucasians from the HyperPATH multicenter study, and 810 Hispanic participants from the HTN-IR cohort. RESULTS: Minor allele carriers...
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