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Article

Apg-2 has a chaperone-like activity similar to Hsp110 and is overexpressed in hepatocellular carcinomas.

FEBS letters - 27 Feb 2004

Gotoh Kazuhisa, Nonoguchi Kohsuke, Higashitsuji Hiroaki, Kaneko Yoshiyuki, Sakurai Toshiharu, Sumitomo Yasuhiko, Itoh Katsuhiko, Subjeck John R, Fujita Jun

Abstract excerpt

Hepatocellular carcinoma (HCC) is the fifth most common cancer in the world. We constructed subtracted cDNA libraries enriched with genes overexpressed in HCCs. Among the 17 genes identified were molecular chaperones, Hsp110, Hsp90B, and Hsp70-1. Expression of the Hsp110 family members was further analyzed, and increased transcript levels of Hsp110 and Apg-2, but not Apg-1, were found in 12 and 14, respectively,...

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Identifiers

PMID: 14987991
DOI: 10.1016/S0014-5793(04)00034-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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