Article
Differential expression of parental alleles of BRCA1 in human preimplantation embryos.
European journal of human genetics : EJHG - 1 Jan 2016
Tulay Pinar, Doshi Alpesh, Serhal Paul, SenGupta Sioban B
Abstract excerpt
Gene expression from both parental genomes is required for completion of embryogenesis. Differential methylation of each parental genome has been observed in mouse and human preimplantation embryos. It is possible that these differences in methylation affect the level of gene transcripts from each parental genome in early developing embryos. The aim of this study was to investigate if there is a parent-specific...
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